Hematopoietic Stem Cell Transplantation for Multiple Myeloma: Guidelines from the American Society for Blood and Marrow Transplantation.

نویسندگان

  • Nina Shah
  • Natalie Callander
  • Siddhartha Ganguly
  • Zartash Gul
  • Mehdi Hamadani
  • Luciano Costa
  • Salyka Sengsayadeth
  • Muneer Abidi
  • Parameswaran Hari
  • Mohamad Mohty
  • Yi-Bin Chen
  • John Koreth
  • Heather Landau
  • Hillard Lazarus
  • Helen Leather
  • Navneet Majhail
  • Rajneesh Nath
  • Keren Osman
  • Miguel-Angel Perales
  • Jeffrey Schriber
  • Paul Shaughnessy
  • David Vesole
  • Ravi Vij
  • John Wingard
  • Sergio Giralt
  • Bipin N Savani
چکیده

Therapeutic strategies for multiple myeloma (MM) have changed dramatically over the past decade. Thus, the role of hematopoietic stem cell transplantation (HCT) must be considered in the context of this evolution. In this evidence-based review, we have critically analyzed the data from the most recent clinical trials to better understand how to incorporate HCT and when HCT is indicated. We have provided our recommendations based on strength of evidence with the knowledge that ongoing clinical trials make this a dynamic field. Within this document, we discuss the decision to proceed with autologous HCT, factors to consider before proceeding to HCT, the role of tandem autologous HCT, post-HCT maintenance therapy, and the role of allogeneic HCT for patients with MM.

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عنوان ژورنال:
  • Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

دوره 21 7  شماره 

صفحات  -

تاریخ انتشار 2015